Uncertainties Associated with Direct Thyroid Measurements Using an NaI(Tl) Survey Meter: the Effect of Anatomical Differences among Individuals.

Photon detectors utilised for direct thyroid measurements to determine the radioiodine content in the thyroid are normally calibrated using a phantom that mimics the human neck, including the thyroid. However, such measurements are necessarily subject to uncertainty because of the difference between the phantom and the real human subject and also the morphological differences among individuals. In this study, personal voxel phantoms were created from magnetic resonance images of the necks of 24 adult volunteers (15 males and 9 females), and numerical simulations using these phantoms were performed to examine the variation in a conversion factor (131I kBq in the thyroid per μSv h-1) for a conventional NaI(Tl) survey meter among the individuals and also to confirm the suitability of reference Japanese voxel phantoms as a calibration standard for such measurements. As a result, it was found that the conversion factor obtained from the reference Japanese male (female) phantom was 1.29 (1.18) times larger than the average conversion factor for the male (female) subjects, suggesting that the conversion factors of the reference Japanese adult male and female phantoms would generally overestimate the 131I thyroidal contents and that the thyroid volume would be one of the factors influencing the conversion factor. This study also revealed a wide difference in the thyroid volume among individuals, which would be of concern when performing specific dose assessments for heavily exposed persons.