Photobiomodulation and Orthodontic Treatment with Clear Aligners: A Case Report of Severe Crowding and Agenesis

This paper aims to demonstrate the effectiveness of photobiomodulation in accelerating orthodontic treatment with clear aligners in correcting an orthodontic malocclusion characterized by severe crowding and agenesis in an adult subject. An adult male patient with Class I malocclusion, a mild Class III skeletal base and severe crowding was treated with 88 Invisalign® (Align Technology, Santa Clara, CA, USA) pairs of aligners replaced every 5 days in combination with an Orthopulse™ (Biolux Research, Vancouver, BC, Canada) photobiomodulation device for home use by the patient. The total orthodontic treatment time was 440 days. Orthopulse™ is a photobiomodulation device that generates continuous beams of near-infrared light (NIR—near-infrared) with a wavelength of 850 nm and a power of 42 mW/cm2 to produce an average energy density on the surface of the silicone impression of 9.3 J/cm2. The combined use of clear aligners and the Orthopulse™ device allowed the patient to replace the aligners according to an experimental 5-day protocol to speed up the orthodontic therapy and, thus, resolve the malocclusion in less time than the manufacturer’s standard.