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Microglial-Targeted Nsmase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice

Meixiang Huang,Carolyn Tallon,Xiaolei Zhu,Kaitlyn D. J. Huizar,Silvia Picciolini,Ajit G. Thomas,Lukas Tenora,Wathsala Liyanage,Francesca Roda,Alice Gualerzi,Rangaramanujam M. Kannan,Marzia Bedoni,Rana Rais,Barbara S. Slusher

Pharmaceutics（2023）

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关键词
Alzheimer's disease,DPTIP,hydroxyl PAMAM dendrimer,D-DPTIP,extracellular vesicles,neutral sphingomyelinase 2,tau
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