Impact of SPARC expression on treatment response of pembrolizumab and brain metastasis in patients with metastatic non-small cell lung cancer.

Sabin Goktas Aydin,Ahmet Bilici, Elif Calis,Yasin Kutlu,Jamshid Hamdard,Harun Muglu,Omer Fatih Olmez,Ebru Karci,Ozgur Acikgoz

International immunopharmacology（2023）

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摘要

Our study sheds light on a novel aspect of SPARC expression as a potential predictor of pembrolizumab response and a marker for CNS progression in metastatic NSCLC patients treated in the first-line setting.

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关键词

Non-small cell lung cancer,SPARC expression,Pembrolizumab,Response

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