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Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).

Tatyana Bodrug,Kaeli A Welsh,Derek L Bolhuis,Ethan Paulаkonis,Raquel C Martinez-Chacin,Bei Liu,Nicholas Pinkin,Thomas Bonacci,Liying Cui,Pengning Xu,Olivia Roscow,Sascha Josef Amann,Irina Grishkovskaya,Michael J Emanuele,Joseph S Harrison,Joshua P Steimel,Klaus M Hahn, Wei Zhang,Ellen D Zhong,David Haselbach,Nicholas G Brown

Nature structural & molecular biology（2023）

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