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Target Occupancy and Functional Inhibition of JAK3 and TEC Family Kinases by Ritlecitinib in Healthy Adults: an Open-Label, Phase 1 Study.

David A. Martin,Jean-Baptiste Telliez,Susan Pleasic-Williams,Ying Zhang,Brendan Tierney,Matthew Blatnik,Jeremy D. Gale,Chris Banfield, Yifan Zhou,Alexandre Lejeune,Samuel H. Zwillich,Erin Stevens, Neeraj Tiwari,Elizabeth Kieras, Ashwin Karanam

Journal of clinical pharmacology（2023）

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关键词
BTK,JAK inhibitor,pharmacodynamics,ritlecitinib,TEC
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