Cystine/glutamate antiporter System x c - deficiency impairs insulin secretion in mice.

Axel de Baat,Daniel T Meier,Leila Rachid,Adriano Fontana,Marianne Böni-Schnetzler,Marc Y Donath

Diabetologia（2023）

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摘要

These findings suggest that System x is required for glutathione maintenance and insulin production in beta cells and that the system is dispensable for islet macrophage function.

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