Application of polyglycolic acid sheets and basic fibroblast growth factor to prevent esophageal stricture after endoscopic submucosal dissection in pigs.

Yusuke Nishimura,Masayoshi Ono,Naoto Okubo,Takayuki Sone,Masayuki Higashino,Shogo Matsumoto,Marina Kubo,Keiko Yamamoto,Shoko Ono,Shunsuke Ohnishi,Naoya Sakamoto

Journal of gastroenterology（2023）

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摘要

Stenosis after esophageal ESD is related to fibrosis in the acute phase. Administration of PGA and bFGF suppresses myofibroblast activation in the acute phase, thereby preventing esophageal constriction in pigs.

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关键词

Basic fibroblast growth factor, Polyglycolic acid, Esophageal stricture, Endoscopic submucosal dissection

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