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T Regulatory Cells, the Evolution of Targeted Immunotherapy

Biochimica et biophysica acta Reviews on cancer/Biochimica et biophysica acta, CR Reviews on cancer(2010)

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Abstract
T regulatory cells are able to suppress anti-tumour immunity in pre-clinical models and in patients. This review highlights the important discoveries in Treg immunology critical to the evolution of targeted immunotherapy. We also describe the therapeutic applications that are currently being assessed and their future potential.
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