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    • Impact of Successful Secondary Hyperparathyroidism Treatment on Cardiovascular Morbidity in Patients with Chronic Kidney Disease KDIGO Stages G3b-5

    Francesca Da Canal,Eva Breuer,Kerstin Hübel,Fran Mikulicic,Ronny R. Buechel,Olivier de Rougemont,Harald Seeger,Diana Vetter

    BRITISH JOURNAL OF SURGERY（2023）

    Cantonal Hospital of Baden | University Hospital Zurich (USZ) | University Hospital Zurich

    Cited 0|Views21
    Abstract
    Chronic kidney disease is common, with a projected increase to 5.4 million people in need of kidney replacement therapy by 2030. As many as 61.7
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    Key words
    Cardiovascular morbidity,Chronic kidney disease,Secondary hyperparathyroidism
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    • Pretraining has recently greatly promoted the development of natural language processing (NLP)
    • We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
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    【要点】：研究探讨了成功治疗继发性甲状旁腺功能亢进对慢性肾病III B-V期患者心血管疾病发病率的影响，发现控制不佳的继发性甲状旁腺功能亢进与心血管疾病发病率增加显著相关。
    

    【方法】：采用回顾性单中心分析，对2015至2019年间在苏黎世大学医院接受冠状动脉钙化评分的211名慢性肾病III B-V期患者进行研究。
    

    【实验】：患者在冠状动脉钙化评分时及6-12个月前评估继发性甲状旁腺功能亢进的存在及控制情况，通过心脏超声获取左心室射血分数(LVEF)和左心室肥厚(LVH)的信息，通过多变量分析评估急性冠状动脉综合征(ACS)和LVH的独立预测因素。结果显示，控制不佳的继发性甲状旁腺功能亢进组与无或控制良好的继发性甲状旁腺功能亢进组相比，LVEF显著降低，LVH更明显，ACS风险显著增加。