Therapeutic Path to Triple Knockout: Investigating the Pan-inhibitory Mechanisms of AKT, CDK9, and TNKS2 by a Novel 2-Phenylquinazolinone Derivative in Cancer Therapy- an In-silico Investigation Therapy

Xylia Q. Peters,Ghazi Elamin,Aimen Aljoundi,Mohamed Issa Alahmdi,Nader E. Abo-Dya,Peter A. Sidhom,Ahmed M. Tawfeek,Mahmoud A. A. Ibrahim,Opeyemi Soremekun,Mahmoud E. S. Soliman

CURRENT PHARMACEUTICAL BIOTECHNOLOGY（2024）

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关键词
2-(4-aminophenyl)-7-chloro-3H-quinazolin-4-one,AKT,CDK9,TNKS2,in silico,inhibitory,flexibility
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