Single-cell analysis characterizes PLK1 as a promoter of immunosuppressive tumor microenvironment in LUAD.

Yifan Kong,Chaohao Li,Jinpeng Liu,Min Zhang,Derek B Allison, Faisal Hassan,Daheng He,Xinyi Wang,Fengyi Mao,Qiongsi Zhang,Yanquan Zhang,Zhiguo Li,Sai Wu,Chi Wang,Xiaoqi Liu

bioRxiv : the preprint server for biology（2023）

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摘要

The characterization of PLK1 as a promoter of immunosuppressive tumor microenvironment enhances our understanding of PLK1's role in anti-tumor immunity and supports the idea of targeting PLK1 in cancer treatment.

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