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The Value of the Second QuantiFERON-TB Gold-Plus Antigen Tube at Diagnosis and at Treatment Completion in Spanish Children with Tuberculosis.

˜The œPediatric infectious disease journal/˜The œpediatric infectious disease journal(2023)

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摘要
We studied 295 children (tuberculosis disease, n = 159; latent tuberculosis infection, n = 136) with positive QuantiFERON-TB Gold-Plus assay results. No significant differences between first and second antigen tube interferon-gamma responses were detected, irrespective of patient and disease characteristics at diagnosis. Of patients with a repeat assay after treatment completion (n = 65), only 16.9% converted to negative results.
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关键词
CD8 T-cell,interferon-gamma release assay,latent tuberculosis,treatment monitoring,tuberculosis
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