Safe Transport of Organs and Tissues for Transplants: Technological Innovation Product Validation Method

Brazil is a country with expressiveness and relevance in the organ and tissue donation and transplantation scenarios.Numerical indicators regarding the rate of transplants demonstrated this importance.During 2021, 23,929 cells, tissues, and organs transplants were performed 1 .However, despite this numerical indicator, the waiting list for transplantation is still lengthy.During the first semester of 2022, 51,674 people were registered waiting for the treatment, which often means a chance for continue living 2 .Due to the difference between the number of transplants and the number of people on the waiting list, strategies are developed to look for problems and failures in the cells, tissues, and organs donation and transplantation processes, as well as improvement opportunities.Regarding these strategies, it was identified that organs and tissues were lost ofdue to logistical problems.According to the Brazilian Association of Organ Transplantation (Associação Brasileira de Transplantes de Órgãos -ABTO), in 2022, 15% of the organs offered were not transplanted for various reasons.Some of these reasons were related to fragilities during the packaging for transport 2 .Currently, the organs are packaged in three primary packages and then in a thermal box filled with ice for transport 3 .Identification is done with labels standardized in current legislation 4 , and the internal temperature is not controlled.Furthermore, the packaging route is not shared.The problems with this type of transport are related to the lack of temperature control, causing the organs to freeze when in contact with the ice or, due to the thawing of the ice, the temperature increase.Both situations result in tissue death and, thus, there is not control over the quality of the transplanted organ.