Seizure reduction in TSC2-mutant mouse model by an mTOR catalytic inhibitor.
Sameer C Dhamne,Meera E Modi,Audrey Gray,Simone Bonazzi,Lucas Craig,Elizabeth Bainbridge,Lahin Lalani,Chloe E Super,Samantha Schaeffer,Ketthsy Capre,Danuta Lubicka,Guiqing Liang,Doug Burdette,Stephanie M McTighe,Sarika Gurnani,Sheryl Anne D Vermudez,Daniel Curtis,Christopher J Wilson,Mustafa Q Hameed,Angelica D'Amore,Alexander Rotenberg,Mustafa Sahin Annals of clinical and translational neurology(2023)
摘要
Novel mTOR catalytic inhibitor TC1 exhibits a promising therapeutic option in the treatment of TSC.
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