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Percutaneous Transforaminal Endoscopic Surgery (PTES) and Mini-Incision L5/S1 OLIF with a Self-Lock Cage for the Surgical Treatment of L5 Spondylolisthesis.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH(2023)

Zhongshan Hospital Fudan University

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Abstract
Abstract Objectives We reported thirteen cases of percutaneous transforaminal endoscopic surgery (PTES) under local anesthesia and mini-incision L5/S1 OLIF (OLIF51) with a self-lock cage for the treatment of L5 spondylolisthesis. Methods From Jan 2019 to Feb 2020, the patients with L5 spondylolisthesis with nerve root symptoms undergoing PTES and OLIF51 were included in this study. PTES under local anesthesia was performed in a prone position, and OLIF51 with a self-lock cage and allograft was then undertaken through a left abdominal mini-incision and oblique retroperitoneal approach between bilateral iliac vessels with the external oblique, internal oblique and transverse abdominal muscles bluntly separated in turn for L5/S1 in a right oblique position under general anesthesia. Back and leg pain were preoperatively and postoperatively evaluated using the VAS, and the clinical outcomes were evaluated with the ODI before surgery and at the 2-year follow-up. The anterior and posterior intervertebral space height (AISH, PISH), lumbar lordotic, and surgical segmental lordotic angle (SLA) were measured on lumbar spine X-rays preoperatively and postoperatively. The fusion status was assessed according to Bridwell’s fusion grades. Results Thirteen cases of L5 spondylolisthesis were included. The operation duration was 49.1 ± 5.6 min for PTES and 73.6 ± 8.2 min for OLIF. There was blood loss of 25 (15–45) ml. The incision length was 7.5 ± 1.1 mm for PTES and 46.8 ± 3.8 mm for OLIF. The hospital stay was 5 (4–6) days, and the follow-up duration was 29 (24–37) months. For the clinical evaluation, the VAS of back and leg pain significantly dropped after surgery (p < 0.001), and the ODI significantly decreased from 64.7 ± 7.8% to 12.9 ± 4.3% 2 years after surgery (p < 0.001). AISH, PISH and SLA significantly improved after surgery (p < 0.05). Fusion grades based on the Bridwell grading system at the 2-year follow-up were grade I in 9 segments (69.2%) and grade II in 4 segments (30.8%). No patients had any form of permanent iatrogenic nerve damage or major complications. No failure of instruments was observed. Conclusions PTES and mini-incision OLIF51 with a self-lock cage is a viable option of minimally invasive surgery for L5 spondylolisthesis, which can achieve direct neurologic decompression, satisfactory fusion and hardly destroys the rectus abdominis and its sheath, paraspinal muscles and bone structures.
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L5 spondylolisthesis,Minimally invasive surgery,Percutaneous transforaminal endoscopic surgery,Oblique lumbar interbody fusion,Mini-incision
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要点】:本文报道了13例采用局部麻醉下的经皮椎间孔内镜手术(PTES)和微小切口L5/S1斜外侧椎间融合术(OLIF51)配合自锁式 cage 治疗L5椎体滑脱的创新方法,并展示了良好的临床效果和融合率。

方法】:研究采用PTES和OLIF51手术方法,PTES在局部麻醉下进行,OLIF51则通过左侧腹部微小切口和斜外侧腹膜后入路,在全身麻醉下完成。

实验】:2019年1月至2020年2月间,13例L5椎体滑脱并伴有神经根症状的患者接受了PTES和OLIF51手术。通过术前和术后VAS评分评估背痛和腿痛,使用ODI评估临床效果,并在腰椎X射线上测量前、后椎间空间高度(AISH、PISH)及手术节段性腰椎前凸角(SLA)。随访29个月(24-37个月),根据Bridwell分级系统评估融合状态。结果显示,术后VAS和ODI显著降低,AISH、PISH和SLA显著改善,融合率为69.2%达到grade I,30.8%达到grade II,无永久性医源性神经损伤或重大并发症发生。