MOESM7 of the Cohesin-Associated Protein Wapal is Required for Proper Polycomb-mediated Gene Silencing

Additional file 7: Figure S6. A) The normalized ChIP-seq tag densities of Ring1b were compared at PcG-marked genes in cells infected with the empty vector (Black) or two separate shRNAs to Wapal (Red). X-axis is the distance in bp around TSS, and y-axis is the normalized tag #. Heat maps are similar to S4. A total of 1,455 PcG-marked genes were used for these analyses. B) Ring1b binding before (Black) or after Wapal depletion (Red) was measured at 1455 genes (same # as in A), which were either expressed at low (left) or high (right) levels. C) Similar to B, but genes where went down (left) or up (right) after depletion of Nanog or Oct4 in ESCs are shown.