Histopathologic Features to Identify a Filler Material Reaction in Oral Pathology. Literature..

ABSTRACT. Background: Filler materials injections in orofacial tissues is a practice that grows annually and may be followed by a reaction involved from small inflammatory nodules to large and diffuse granulomas, it’s may develop month or years after de procedure, making it difficult the diagnosis. Objectiv e: Identify histopathological features of a reaction to materials filler through a literature review and report three cases in orofacial region. Method: We made an exhaustive investigation of scientific articles related with filler materials commonly used in orofacial region and clinical cases of foreign body reaction by filler material with emphasis in the histopathological features. The search was made in the database PubMed and Scholar Google from the 2004 - 2015 period. Additionally, we collect three cases diagnosed as foreign body reaction by exogenous material in oral pathology laboratory of Anzoategui state, Venezuelan. Results: We found just 10 articles with clinical cases and its histopathological features. Other 3 review articles explain specific characteristics for each filler material. Based on this review, we confirm the 3 cases presented. Conclusions: Few studies describe the histopathological features of a filler material reaction and the kind of material; nevertheless, were synthesized for the confirmation of cases.