Immunomodulatory Properties of Packed Red Blood Cells during Storage.

Eva Laurén, Lotta Sankkila,Ville Pettilä,Erja Kerkelä

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie（2023）

Cited 0|Views8

No score

Abstract

This in vitro study demonstrates that stored RBC SN will have mixed immunomodulatory effects depending on responder cells and conditions, independent of RBC storage age. Fresh RBCs containing relatively few EVs can induce immune responses. Residual plasma in the products may contribute to these effects.

Translated text

Key words

Red blood cells, Extracellular vesicles, T-cell proliferation, Transfusion-related immunomodulation

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined