Cine MRI-based Analysis of Intrafractional Motion in Radiation Treatment Planning of Head and Neck Cancer Patients.

Yonatan Weiss,Lee Chin, Eyesha Younas,Kaiming Guo, Christopher Dydula,Allan Hupman,Angus Lau,Zain A Husain,Andrew J Bayley,Kevin Higgins,Danny Enepekides,Antoine Eskander,Ling Ho,Ian Poon,Irene Karam

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology（2023）

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Abstract

The use of MR-cine in treatment planning allows for quantification of tumor motion during swallow and resting periods and should be accounted for during treatment planning. With motion considered, the derived margins may exceed the commonly used 3-5 mm PTV margins . Quantification and analysis of tumor and patient-specific PTV margins is a step towards real-time MRI guidance adaptive radiotherapy.

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Key words

Head and neck cancer,MRI cine,Radiation oncology,Medical physics,PTV margins,Radiotherapy

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