Serum sPD-L1 levels are elevated in patients with viral diseases, bacterial sepsis or in patients with impaired renal function compared to healthy blood donors.

Lorin Loacker, Alexander Egger,Vilmos Fux,Rosa Bellmann-Weiler,Günter Weiss,Andrea Griesmacher,Gregor Hoermann,Franz Ratzinger,Helmuth Haslacher,Hubert Schrezenmeier,Markus Anliker

Clinical chemistry and laboratory medicine（2023）

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摘要

sPD-L1 serum levels are significantly elevated in patients with sepsis, influenza, mesasles, Dengue fever or SARS-CoV2. Highest levels are detectable in patients with measles and Dengue fever. Also impaired renal function causes an increase in levels of sPD-L1. As a consequence, renal function has to be taken into account in the interpretation of sPD-L1 levels in patients.

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关键词

Gram negative, Gram positive, renal function, sepsis, sPD-L1, viral infections

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