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MEPicides: Α,β-Unsaturated Fosmidomycin N-Acyl Analogs As Efficient Inhibitors of Plasmodium Falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase.

Xu Wang,Rachel L. Edwards,Haley S. Ball,Kenneth M. Heidel,Robert C. Brothers,Claire Johnson,Amanda Haymond,Misgina Girma,Allyson Dailey,Jose Santinni Roma,Helena I. Boshoff,Damon M. Osbourn, Marvin J. Meyers,Robin D. Couch,Audrey R. Odom John,Cynthia S. Dowd

ACS INFECTIOUS DISEASES（2023）

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关键词
Plasmodium falciparum,MEP pathway,DXR,antibiotic,antimalarial,phosphonateprodrug
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