Rapidly Progressive Visual Field Deterioration in a Glaucomatous Patient Treated with Several Anti-VEGF Injections for Neovascular AMD: A Case Report

One of the recognized side effects of intravitreal anti-VEGF injections (IVIs) is the elevation of intraocular pressure (IOP) [4–6]. Although transient and related mainly to an increase in intraocular volume, the increase of IOP has a negative effect on changes in the thickness of the peripapillary nerve fiber layer [7, 8] and seems to be more deleterious in glaucoma patients who already show optic nerve damage and in which IOP spikes take longer to return to basal levels (where normal IOP values are considered between 10 and 21mmHg) [9]. Moreover, an increase in IOP following IVI is associated with a significant reduction in optic nerve perfusion [10,11].