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Phase 1/2a Clinical Trial in ALS with Ropinirole, a Drug Candidate Identified by Ipsc Drug Discovery

Satoru Morimoto,Shinichi Takahashi,Daisuke Ito,Yugaku Date,Kensuke Okada,Chris Kato,Shiho Nakamura,Fumiko Ozawa,Chai Muh Chyi,Ayumi Nishiyama,Naoki Suzuki,Koki Fujimori, Tosho Kondo,Masaki Takao,Miwa Hirai,Yasuaki Kabe,Makoto Suematsu,Masahiro Jinzaki,Masashi Aoki, Yuto Fujiki,Yasunori Sato,Norihiro Suzuki,Jin Nakahara,Hideyuki Okano

Cell stem cell（2023）

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Key words
amyotrophic lateral sclerosis,ALS,ropinirole hydrochloride,dopamine D2 receptor agonist,iPSC drug discovery,translational research,phase 1/2a trial,PRO-ACT registry data,reverse translational research,cholesterol synthesis
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