Loop-extruding Smc5/6 Organizes Transcription-Induced Positive DNA Supercoils

Kristian Jeppsson,Biswajit Pradhan,Takashi Sutani,Toyonori Sakata,Miki Umeda Igarashi,Davide Giorgio Berta,Takaharu Kanno,Ryuichiro Nakato,Katsuhiko Shirahige,Eugene Kim,Camilla Bjorkegren

MOLECULAR CELL（2024）

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关键词

Smc5/6,cohesin,DNA loop extrusion,DNA supercoiling,3D chromosome organization,convergent transcription,DNA plectoneme,single-molecule analysis,Hi-C,ChIP-seq

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