Discovery of Pyrrolo[2,1- F ][1,2,4]Triazine-Based Inhibitors of Adaptor Protein 2-Associated Kinase 1 for the Treatment of Pain
Carolyn D. Dzierba,Bireshwar Dasgupta, George Karageorge,Walter Kostich,Brian Hamman,Jason Allen, Kim M. Esposito,Ramesh Padmanabha,James Grace,Kimberley Lentz,John Morrison,Daniel Morgan,Amy Easton,Clotilde Bourin, Marc R. Browning,Ramkumar Rajamani,Andrew Good,Dawn D. Parker,Jodi K. Muckelbauer,Javed Khan,Daniel Camac,Kaushik Ghosh,Vivek Halan,Jonathan S. Lippy,Kenneth S. Santone,R. Rex Denton,Ryan Westphal,Linda J. Bristow,Charles M. Conway,Joanne J. Bronson,John E. Macor Medicinal chemistry research（2023）
关键词
Adaptor protein 2-associated kinase 1,AAK1,Neuropathic pain,Kinase inhibitor
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