COVID-19 and Catatonia: Prevalence, Challenges, Pathophysiology, and Treatment

Joan Oh,Puneet Chawla Sahota, Tarannum Mohammadi,Basant K. Pradhan,Maju Mathew Koola

ANNALS OF CLINICAL PSYCHIATRY（2023）

Cited 3|Views0

Abstract

BACKGROUND: Emerging literature supports the association between acute COVID-19 infection and neuropsychiatric complications. This article reviews the evidence for catatonia as a potential neuropsychiatric sequela of COVID-19 infection.METHODS: PubMed was searched using the terms catatonia, severe acute respiratory syndrome coronavirus 2, and COVID-19. Articles were lim-ited to those published in the English language between 2020 and 2022. Forty-five articles that specifically studied catatonia associated with acute COVID-19 infection were screenedRESULTS: Overall, 30% of patients with severe COVID-19 infection devel-oped psychiatric symptoms. We found 41 cases of COVID-19 and catato-nia, with clinical presentations that varied in onset, duration, and severity. One death was reported in a case of catatonia. Cases were reported in patients with and without a known psychiatric history. Lorazepam was successfully used, along with electroconvulsive therapy, antipsychotics, and other treatments.CONCLUSIONS: Greater recognition and treatment of catatonia in individ-uals with COVID-19 infection is warranted. Clinicians should be familiar with recognizing catatonia as a potential outcome of COVID-19 infec-tion. Early detection and appropriate treatment are likely to lead to bet -ter outcomes.

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Post-acute COVID-19 Syndrome

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Pretraining has recently greatly promoted the development of natural language processing (NLP)
We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
We propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generation
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