Neuroradiological Value of High Resolution Magnetic Resonance Neurography (MRN) in the Diagnosis of Sciatic Neuropathy Presumably Related to COVID-19

Background: In the context of sciatic neuropathy, there have been many etiologies and the need for differentiating between the possible underlying causes is an important matter for early diagnosis and management. COVID-19 has been associated with many peripheral neuropathies and sciatic neuropathy could be potentially a complication. Although, very rare with limited cases published in the literature to date. Methods: We investigated the role of MR neurography in evaluating sciatic neuropathy presumably post- COVID-19 infection in one of our cases after exclusion of other possible causes of sciatic neuropathy using STIR MR neurography. Results: Our STIR MR neurography demonstrated increased signal and size of the left sciatic nerve with 2ry muscular edema in the biceps femoris muscle in keeping radiologically with sciatic neuropathy. Conclusion: MR neurography has proven to be valuable in narrowing the differential diagnosis of the reported imaging findings and showed a very good correlation to the NCVs, laboratory investigations, and sural nerve biopsy. Although a very rare complication, COVID-19 could be a potential direct cause of sciatic neuropathy.