Gold Nanoparticle Enabled Localized Surface Plasmon Resonance on Unique Gold Nanomushroom Structures for On‐Chip CRISPR‐Cas13a Sensing (adv. Mater. Interfaces 1/2023)

Jacob Waitkus, Yu Chang,Li Liu,Srinivasu Valagerahally Puttaswamy,Taerin Chung,Adrian M. Molina Vargas,Stephen J. Dollery,Mitchell R. O'Connell,Haogang Cai,Gregory J. Tobin,Nikhil Bhalla,Ke Du

Advanced materials interfaces（2023）

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摘要

Optical Nano-Biosensors An optical nanobiosensor is reported in article number 2201261 by Jacob Waitkus and co-workers. Localized surface plasmon resonance (LSPR) allows for sensitive detection of alterations to the local refractive index surrounding unique gold nanomushroom structures. The resultant novel device is extended to combine with a CRIPSR-Cas13a assay for specific viral detection of target RNA.

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