A Clinical Case of Composite Pheochromocytoma in a Child and a Literature Review

Composite pheochromocytoma (CPh) is a rare malignant neoplasm that occurs in different age ranges. The main treatment for pheochromocytoma is a complete surgical removal of the tumor, while in the case of neuroblastoma, risk-adapted therapy is used, depending on the risk group, including chemotherapy, autologous bone marrow transplantation, radiation therapy, immunotherapy and 131 I-metaiodbenzylguanidine therapy. Due to the rarity of CPh, there are no standard approaches to systemic therapy. The tactics and extent of treatment are determined according to the predominance of the tumor malignant component. This article presents a rare case of the development of composite pheochromocytoma with poorly differentiated neuroblastoma of the left adrenal gland in a 4-year-old child. The patient’s parents gave consent to the use of their child’s data, including photographs, for research purposes and in publications.