Engineering H₂O₂ and O₂ Self‐Supplying Nanoreactor to Conduct Synergistic Chemiexcited Photodynamic and Calcium‐Overloaded Therapy in Orthotopic Hepatic Tumors (Adv. Healthcare Mater. 20/2022)

Photodynamic Therapies In article 2201613 by Chia-Hao Su, Chen-Sheng Yeh, and co-workers, the concept of self-supplying H2O2 and O2 is presented by an all-in-one nanoreactor to process H2O2 and O2 generation, chemiluminescence resonance energy transfer (CRET) activated by the generated H2O2, and energy-transfer to excite photosensitizer resulting in singlet oxygen formation. This allows the conduction of an external light-fee CRET-mediated photodynamic therapy, ushering in a new era in light-based therapeutic interventions.