Supplementary Figures S1-S5 from Genetic Deletion of AEG-1 Prevents Hepatocarcinogenesis

Generation of AEG-1KO mouse (S1); Analysis of spleen cells of adult WT and AEG-1KO mice (S2); F4/80 staining for macrophages in spleen sections of aged (16 m) WT and AEG-1KO mouse. Magnification 400X (S3); Graphical representation of quantification of F4/80 staining for macrophages in liver sections of WT and AEG-1KO mice, either untreated (naïve) or treated with DEN or DEN/PB (S4); Stellate cells are activated in the tumor region of WT liver (S5).