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Supplementary figures S1-S8 from Deletion of Interstitial Genes between <i>TMPRSS2</i> and <i>ERG</i> Promotes Prostate Cancer Progression

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摘要

Supplementary Figures: Figure S1. Syntenic regions between human chromosome 21q and mouse chromosome 8q. Figure S2. IHC staining of prostate lesions in Pb-Cre;T-ERG;PtenL/L and Pb-Cre;T-3Mb-Erg;PtenL/L mouse models. Figure S3. Overview of mouse prostate tissues microdissected for genomic DNA PCR analysis and microarray expression profiling. Figure S4. Cre-mediated deletion of the interstitial region in T-delta-Erg/Pten-null lesions. Figure S5. Additional data showing the EMT phenotype in prostate lesions developed in Pb-Cre;T-3Mb-Erg;PtenL/L mice. Figure S6. Expression analysis of AR target genes in T-∆-Erg/Pten-null and Ras/Pten prostate tumors. Figure S7. Expression analysis of select ETS factor genes in prostate tissues. Figure S8. Expression analysis of interstitial genes in T-delta-Erg/Pten-null versus Pten-null HG-PIN lesions.

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