Supplementary Figures with legends from <i>SATB2-AS1</i> Suppresses Colorectal Carcinoma Aggressiveness by Inhibiting SATB2-Dependent <i>Snail</i> Transcription and Epithelial–Mesenchymal Transition

Supplementary Figures S1 through S11. (1) Supplementary Figure S1 shows the ectopical overexpressing of SATB2-AS1 in two CRC cell lines by lentivirus delivery. (2) Supplementary Figure S2 shows the effect of SATB2-AS1 on apoptosis in CRC cells. (3) Supplementary Figure S3 shows the effect of SATB2-AS1 knockdown mediated by siRNA on CRC cell proliferation, invasion and migration in vitro. (4) Supplementary Figure S4 shows the expression levels of SATB2 mRNA in CRC and adjacent non-cancerous tissues. (5) Supplementary Figure S5 shows the regulatory effect of SATB2-AS1 expression by SATB2. (6) Supplementary Figure S6 shows the effect of SATB2-AS1 on SATB2 mRNA stability. (7) Supplementary Figure S7 shows the enrichment amount of ZEB1-AS1 and PACER RNA with the p300 antibody by RIP assay. (8) Supplementary Figure S8 shows the regulatory effect of SATB2-AS1 on p300 mRNA. (9) Supplementary Figure S9 shows the inhibitory effects of SATB2-AS1 on M5 cells requiring p300 and SATB2. (10) Supplement Figure S10 shows the occupancy ability of p300 on Snail promoter by ChIP assay. (11) Supplementary Figure S11 shows the regulatory effect of Snail on SATB2-AS1 expression.