Synthesis, in Silico Analysis, and Larvicidal Activity of New Bis-oxadiazole Derivatives
Russian journal of organic chemistry(2023)
摘要
Twelve new 2,2′-bi(1,2,4-oxadiazole) derivatives containing heterocyclic and long-chain substituents have been synthesized by the condensation of aldehyde azines and oximes. In silico studies of these compounds revealed their good drug likeness and drug score. Some of the synthesized compounds showed moderate to excellent larvicidal activity.
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关键词
aldehyde azines,oximes,bis-oxadiazoles,in silico studies,larvicidal activity
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