The spontaneous immortalization probability of mammalian cell culture strains, as their proliferative capacity, correlates with species body mass, not longevity

Matteo Perillo,Angela Punzo,Cristiana Caliceti,Christian Sell,Antonello Lorenzini

Biomedical Journal（2023）

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摘要

The relation between immortalization and body mass suggests a need to evolve stringent mechanisms that control genetic stability during the evolution of a large body mass.

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关键词

spontaneous immortalization probability,longevity,mammalian cell culture,proliferative capacity

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