Oral Cancer Pain Includes Thermal Allodynia That May Be Attenuated by Chronic Alcohol Consumption.

Cara B Gonzales,Jorge J De La Chapa,Amol M Patwardhan,Kenneth M Hargreaves

Pharmaceuticals (Basel, Switzerland)（2023）

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Abstract

Oral cancer patients experience multiple types of cancer pain, including thermal allodynia. Alcohol consumption correlates with reduced OSCC pain and reduced thermal allodynia, which may be mediated by TRPA1 and TRPV1. Hence, reduced pain in these patients may contribute to a delay in seeking care, and thus a delay in early detection and treatment.

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Key words

alcohol drinking habits,analog pain scale,cancer-related pain,oral squamous cell carcinoma,patient reported outcomes,thermal pain

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