Impact of Respiratory Bacterial Infections on Mortality in Japanese Patients with COVID-19: a Retrospective Cohort Study.

Kensuke Nakagawara,Hirofumi Kamata，Takanori Kanai,Koichi Fukunaga

BMC pulmonary medicine（2023）SCI 3区

Cited 8|Views93

Abstract

Although cases of respiratory bacterial infections associated with coronavirus disease 2019 (COVID-19) have often been reported, their impact on the clinical course remains unclear. Herein, we evaluated and analyzed the complication rates of bacterial infections, causative organisms, patient backgrounds, and clinical outcome in Japanese patients with COVID-19. We performed a retrospective cohort study that included inpatients with COVID-19 from multiple centers participating in the Japan COVID-19 Taskforce (April 2020 to May 2021) and obtained demographic, epidemiological, and microbiological results and the clinical course and analyzed the cases of COVID-19 complicated by respiratory bacterial infections. Of the 1,863 patients with COVID-19 included in the analysis, 140 (7.5

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Key words

SARS-CoV-2 infection,Neutrophil–lymphocyte ratio,Mortality,Invasive mechanical ventilation,Intensive care unit

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