The Lessebo Effect in Disease Modification Trials in Parkinson's Disease.

Tiago A Mestre,Michael P McDermott,Raquel Lobo,Joaquim J Ferreira,Anthony E Lang

Movement disorders : official journal of the Movement Disorder Society（2023）

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摘要

We did not observe the lessebo effect in DMT. The necessary use of a placebo (and no active comparator) is a limitation. The prospective measurement of expectation of benefit could help to evaluate the many impacts of placebo use. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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关键词

Parkinson's disease,clinical trial,disease modification,expectation,lessebo,placebo

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