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Influence of timing of maternal pertussis immunization on the avidity of transferred antibodies in term and preterm neonates.

Julie Sartoretti,Paola Fontannaz,Begoña Martinez de Tejada,Véronique Othenin-Girard, Antonina Chilin,Barbara Lemaître,Géraldine Blanchard-Rohner,Claire-Anne Siegrist,Christiane S Eberhardt

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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Abstract
The timing of maternal pertussis vaccination influences the titers of cord-blood anti-pertussis antibodies. Whether it affects their avidity is unknown. We demonstrate in 298 term and 72 preterm neonates that antibody avidity is independent of the timing of maternal vaccination, whether comparing 2nd with 3rd trimester or intervals before birth.
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Maternal pertussis vaccination,antibody transfer,avidity,preterm neonates,term neonates
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