Common and Distinct Effects of Incentives on Spatial Working Memory in Schizophrenia and Obsessive-Compulsive Disorder

Christina Sarantopoulos, Doah E. Shin,Charles H. Schleifer,Flora Moujaes,Brendan Adkinson,Jie Lisa Ji, Antonija Kolabaric,Morgan Flynn,Nicole Santamauro,John H. Krystal,John D. Murray,Grega Repovs,William J. Martin,Christopher Pittenger,Alan Anticevic,Youngsun Cho

Biological Psychiatry（2023）

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摘要

Patients with schizophrenia (SCZ) and patients with OCD share symptomatology, including motivational and cognitive impairments, suggesting common and distinct associated mechanisms. We analyzed data from SCZ, OCD and typical adults (TA) who performed an incentivized spatial working memory (sWM) task.

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关键词

Schizophrenia,OCD,Cognition,Motivation,fMRI

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