Brainstem–cortex Disconnection in Amyotrophic Lateral Sclerosis: Bulbar Impairment, Genotype Associations, Asymptomatic Changes and Biomarker Opportunities

Marlene Tahedl,Ee Ling Tan,Rangariroyashe H. Chipika,Jennifer C. Hengeveld,Alice Vajda, Mark A. Doherty,Russell L. McLaughlin,We Fong Siah,Orla Hardiman,Peter Bede

Journal of Neurology（2023）

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关键词
Amyotrophic lateral sclerosis,Biomarkers,Bulbar dysfunction,Motor neuron disease,Neuroimaging,Clinical trials,MRI
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