Supplementary Figures from E3 Ubiquitin Ligase RNF126 Promotes Cancer Cell Proliferation by Targeting the Tumor Suppressor p21 for Ubiquitin-Mediated Degradation

Figure S1. RNF126 knockdown decreases cell viability in breast cancer cell lines Figure S2. The expression, subcellular localization, stability, and ubiquitination of RNF126 Figure S3. RNF126 knockdown increases p21 protein levels but does not change p21 mRNA levels in both MDA-MB-231 and PC-3 Figure S4. RNF126 knockdown delays the G1/S cell cycle progression in MDA-MB-231 Figure S5. Stable knockdown of RNF126 in SW527 suppresses cell growth in vitro and in vivo Figure S6. Negative expression correlation between RNF126 and p21 in breast cell lines Table S1: Primer sequences used in this study Table S2: siRNA and shRNA target sequences used in this study