Supplementary Video 2 from Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors

Ashley A. Manzoor,Lars H. Lindner,Chelsea D. Landon,Ji-Young Park,Andrew J. Simnick,Matthew R. Dreher,Shiva Das,Gabi Hanna,Won Park,Ashutosh Chilkoti,Gerben A. Koning,Timo L.M. ten Hagen,David Needham,Mark W. Dewhirst

crossref（2023）

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摘要

AVI file - 34.5MB, Real-time intravascular release of doxorubicin from Dox-TSL and subsequent redistribution of drug in B16 melanoma tumor tissue. The video shows drug (red) delivered over the first 20min, at 20x magnification. The eNOS-GFPtg mouse model was used in this experiment, so the blood vessels are green. (Download before playing in IE8)

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