Metabolic Features of Increased Gut Permeability, Inflammation, and Altered Energy Metabolism Distinguish Agricultural Workers at Risk for Mesoamerican Nephropathy

Nathan H. Raines,Dominick A. Leone,Cristina O'Callaghan-Gordo,Oriana Ramirez-Rubio,Juan Jose Amador,Damaris Lopez Pilarte,Iris S. Delgado,Jessica H. Leibler,Nieves Embade,Ruben Gil-Redondo,Chiara Bruzzone,Maider Bizkarguenaga,Madeleine K. Scammell,Samir M. Parikh,Oscar Millet,Daniel R. Brooks,David J. Friedman

METABOLITES（2023）

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Key words

Mesoamerican nephropathy (MeN),chronic kidney disease of unknown etiology (CKDu),chronic kidney disease of nontraditional cause (CKDnt),nicotinamide adenine dinucleotide (NAD+),kynurenate,tryptophan,hippurate,agriculture,manual labor

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