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Identification of Z-Tyr-Ala-CHN2, a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity Against Coronaviruses, Including SARS-CoV-2

Jordi Doijen,Koen Temmerman,Christel van den Eynde,Annick Diels,Nick Van den Broeck,Michiel Van Gool,Inha Heo,Steffen Jaensch,Marleen Zwaagstra, Mayra Diosa Toro,Winston Chiu,Steven De Jonghe,Pieter Leyssen,Denisa Bojkova,Sandra Ciesek,Jindrich Cinatl,Lore Verschueren,Christophe Buyck,Frank Van Kuppeveld,Johan Neyts,Marnix Van Loock,Ellen Van Damme

Microorganisms（2023）

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Key words
cathepsin L inhibitor,coronavirus,in vitro,phenotypic screening,SARS-CoV-2
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