Mitigating the Risk of Antimalarial Resistance Via Covalent Dual-Subunit Inhibition of the Plasmodium Proteasome.
Cell chemical biology(2023)
Key words
Plasmodium falciparum,malaria,proteasome,artemisinin,minimum inoculum of resistance,CRISPR/Cas9 gene editing,conditional knockdown,molecular modeling,covalent inhibitors,drug discovery
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