The combination of astragaloside IV and Panax notoginseng saponins attenuates cerebral ischaemia-reperfusion injury in rats through ferroptosis and inflammation inhibition via activating Nrf2.
The Journal of pharmacy and pharmacology（2023）
Abstract
The findings of this study suggest that combining AST IV and PNS attenuates CIRI by activating Nrf2 to inhibit ferroptosis and inflammatory responses.
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Key words
Panax notoginseng saponins,astragaloside IV,cerebral ischaemia–reperfusion injury,ferroptosis,inflammatory,nuclear factor erythroid 2-related factor 2
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