Elevated creatine kinase is mainly harmless in children but persistent and severe hyperCKaemia should raise suspicions of serious muscle damage

Acta PaediatricaAccepted Articles BRIEF REPORT Elevated creatine kinase is mainly harmless in children but persistent and severe hyperCKaemia should raise suspicions of serious muscle damage Francesca Burlo, Francesca Burlo orcid.org/0000-0002-8915-5855 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorVeronica Grigoletto, Veronica Grigoletto orcid.org/0000-0001-6247-5739 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorSerena Pastore, Corresponding Author Serena Pastore serena.pastore@burlo.trieste.it Department of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Trieste, Italy Correspondence Serena Pastore, Email: serena.pastore@burlo.trieste.it, Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAnna Vaivoda, Anna Vaivoda Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAndrea Trombetta, Andrea Trombetta orcid.org/0000-0003-2092-3067 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorGianluca Tamaro, Gianluca Tamaro Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAndrea Magnolato, Andrea Magnolato Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAlberto Tommasini, Alberto Tommasini orcid.org/0000-0002-6943-7927 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, Italy Department of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Trieste, ItalySearch for more papers by this authorAndrea Taddio, Andrea Taddio Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, Italy Department of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Trieste, ItalySearch for more papers by this author Francesca Burlo, Francesca Burlo orcid.org/0000-0002-8915-5855 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorVeronica Grigoletto, Veronica Grigoletto orcid.org/0000-0001-6247-5739 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorSerena Pastore, Corresponding Author Serena Pastore serena.pastore@burlo.trieste.it Department of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Trieste, Italy Correspondence Serena Pastore, Email: serena.pastore@burlo.trieste.it, Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAnna Vaivoda, Anna Vaivoda Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAndrea Trombetta, Andrea Trombetta orcid.org/0000-0003-2092-3067 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorGianluca Tamaro, Gianluca Tamaro Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAndrea Magnolato, Andrea Magnolato Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, ItalySearch for more papers by this authorAlberto Tommasini, Alberto Tommasini orcid.org/0000-0002-6943-7927 Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, Italy Department of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Trieste, ItalySearch for more papers by this authorAndrea Taddio, Andrea Taddio Department of Medicine, Surgery, and Health Sciences, University of Trieste, Trieste, Italy Department of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Trieste, ItalySearch for more papers by this author First published: 16 March 2023 https://doi.org/10.1111/apa.16755 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. 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