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Discovery of a Brain-Sparing GIRK1/4 Inhibitor for Pharmacological Cardioversion of Atrial Fibrillation

Stefan Peukert, Hatice Belgin Gulgeze Efthymiou,Ruowei Mo, Yunshan Peng,Fupeng Ma,Guillaume Barbe, Gregory Bebernitz,Cary Fridrich, Chiara Buono,Eric T. Williams,Thomas Daniels,Lisha Li, Xia Zhang,Yuichiro Adachi, Mie Abe,Andrew K. P. Taggart

Bioorganic & Medicinal Chemistry Letters（2023）

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关键词
Atrial fibrillation,GIRK1,4 inhibitor,Cardioversion,Peripherally restricted drug
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